IL2 (DM187) Rabbit mAb
$565.00
| Cat.#: 28530 |
| Product Name: Anti-IL2(DM187) Rabbit Monoclonal Antibody |
| Synonyms: IL-2; lymphokine; TCGF |
| Description: Anti-IL2 antibody(DM187) Rabbit Monoclonal Antibody |
| Background: This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4; IL7; IL9; IL15; IL21; erythropoietin; and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4 and CD8 T lymphocytes; that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic; which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease; which suggests an essential role of this gene in the immune response to antigenic stimuli. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit IgG |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human IL2 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 Figure 1. Flow cytometry analysis with Anti-IL2 (DM187) on Expi293 cells transfected with human IL2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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