Human PRAME Protein, hFc Tag
$535.00
| Cat.#: 11710 |
| Product Name: Human PRAME Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: CT130;MAPE;OIP-4;OIP4 |
| Target: PRAME |
| UNIPROT ID: P78395 |
| Description: Recombinant human PRAME protein with C-terminal human Fc tag |
| Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 81.51 kDa after removal of the signal peptide. |
| Molecular Characterization: PRAME (Met1-Asn509) hFc (Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
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