Human IL25 Protein
$535.00
| Cat.#: 12278 |
| Product Name: Human IL25 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: IL17E |
| Target: IL25 |
| UNIPROT ID: Q9H293 |
| Description: Recombinant human IL25 Protein with C-terminal human Fc tag |
| Background: The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 42.9 kDa after removal of the signal peptide. The apparent molecular mass of IL25-hFc is approximately 35-55 kDa due to glycosylation. |
| Molecular Characterization: IL25(Tyr33-Gly177) hFc(Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
 Figure 1. Human IL25 Protein, hFc Tag on SDS-PAGE under reducing condition. |
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