Human IL17RB Protein, hFc Tag
$535.00
| Cat.#: 11618 |
| Product Name: Human IL17RB Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: CRL4;EVI27;IL17BR;IL17RH1 |
| Target: IL17RB |
| UNIPROT ID: Q9NRM6 |
| Description: Recombinant human IL17RB protein with C-terminal human Fc tag |
| Background: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 55.77 kDa after removal of the signal peptide. |
| Molecular Characterization: IL17RB (Arg18-Pro292) hFc(Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
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