Human CD305 Protein, hFc Tag

Name: Human CD305 Protein, hFc Tag
SKU: 11746
Price: 535.00 USD
Availability: InStock

$535.00

Cat.#: 11746

Product Name: Human CD305 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CD305;LAIR-1

Target: CD305

UNIPROT ID: Q6GTX8

Description: Recombinant human CD305 protein with C-terminal human Fc tag

Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 41.36 kDa after removal of the signal peptide.

Molecular Characterization: CD305 (Gln22-Y165) hFc(Glu99-ALA330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

SKU: 11746

Category: C, Dimabio, Extracellular Domain Proteins, Proteins