GITR Ligand (DM52) Rabbit mAb

Name: GITR Ligand (DM52) Rabbit mAb
SKU: 28349
Price: 565.00 USD
Availability: InStock

$565.00

Cat.#: 28349

Product Name: Anti-GITR Ligand(DM52) Rabbit Monoclonal Antibody

Synonyms: TNFSF18; AITRL; TL6; hGITRL; GITR Ligand

Description: Anti-GITR Ligand antibody(DM52) Rabbit Monoclonal Antibody

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18:AITR:GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells; and is thought to be important for interaction between T lymphocytes and endothelial cells.

Applications: ELISA; Flow Cyt

Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100

Host Species: Rabbit

Isotype: Rabbit IgG

Purification: Purified from cell culture supernatant by affinity chromatography

Species Reactivity: Human GITR Ligand

Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Expi 293 cell line transfected with irrelevant protein (A) and human GITR-L (B) were surface stained with Rabbit anti-GITR-L monoclonal antibody 15µg/ml ( clone: DM52) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Figure 2. Flow cytometry data of serially titrated Rabbit anti-GITR-L monoclonal antibody ( clone: DM52) on H929 cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.