AFP (DMC281) IgG1 Chimeric mAb

Name: AFP (DMC281) IgG1 Chimeric mAb
SKU: 28189
Price: 565.00 USD
Availability: InStock

$565.00

Cat.#: 28189

Product Name: Anti-AFP(DMC281) IgG1 Chimeric Monoclonal Antibody

Synonyms: AFPD; FETA; HPAFP

Description: Anti-AFP antibody(DMC281) IgG1 Chimeric Monoclonal Antibody

Background: This gene encodes alpha-fetoprotein; a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma; and has prognostic value for managing advanced gastric cancer. However; hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin; and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms; and binds copper; nickel; fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Applications: Flow Cyt

Recommended Dilutions: Flow Cyt 1:100

Host Species: Rabbit

Isotype: Rabbit:Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Species Reactivity: Human AFP

Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-AFP (DMC281) on Expi293 cells transfected with human AFP (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

SKU: 28189

Category: A, Dimabio, Rabbit Monoclonal Antibodies, Transmembrane Rabbit Monoclonal Antibodies