
Human CD305 Protein, hFc Tag
$535.00
| Cat.#: 11746 |
| Product Name: Human CD305 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: CD305;LAIR-1 |
| Target: CD305 |
| UNIPROT ID: Q6GTX8 |
| Description: Recombinant human CD305 protein with C-terminal human Fc tag |
| Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 41.36 kDa after removal of the signal peptide. |
| Molecular Characterization: CD305 (Gln22-Y165) hFc(Glu99-ALA330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
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