Human TSHR full length protein-PeptiNanodisc

Name: Human TSHR full length protein-PeptiNanodisc
SKU: 11026-1
Price: 5000.00 USD
Availability: InStock

$5,000.00

Cat.#: 11026-1

Product Name: Human TSHR full length protein-PeptiNanodisc

Size : 10 µg, 50 µg and 100 µg

Synonyms: CHNG1; hTSHR-I; LGR3

Target: TSHR

UNIPROT ID: P16473

Description: Human TSHR full length protein-synthetic nanodisc

Background: The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.

Species/Host: HEK293

Molecular Weight: The human full length TSHR protein has a MW of 86.8 kDa

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag TSHR-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TSHR-Nanodisc is 2.108ng/ml.