CD45 (DM193) Rabbit mAb
$565.00
| Cat.#: 28536 |
| Product Name: Anti-CD45(DM193) Rabbit Monoclonal Antibody |
| Synonyms: B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| Description: Anti-CD45 antibody(DM193) Rabbit Monoclonal Antibody |
| Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit IgG |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human CD45 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 Figure 1. Flow cytometry analysis with Anti-CD45 (DM193) on Expi293 cells transfected with human CD45 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
Related products
-
Cdc42 Chicken
$245.00 -
Cdc42 mAb
$255.00 -
Cdc42 pAb
$245.00 -
Cdc42 Protein
$265.00 -
Cdc42 Pull-Down Activation Assay Kit
$745.00
Reviews
There are no reviews yet.