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Human CD26 Protein, hFc Tag

$535.00

Cat.#:     11662
Product Name:   Human CD26 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ADABP;ADCP2;CD26;DPPIV;TP103
Target:    ADABP
UNIPROT ID:    P27487
Description:    Recombinant human CD26 protein with C-terminal human Fc tag
Background:     The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 116.71 kDa after removal of the signal peptide.
Molecular Characterization:    ADABP(Asn29-Pro766) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

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