Human ANGPT2 Protein, hFc Tag
$535.00
| Cat.#: 11604 |
| Product Name: Human ANGPT2 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: ANGPT2;GPT2;NG2;ngiopoietin-2 |
| Target: ANGPT2 |
| UNIPROT ID: O15123 |
| Description: Recombinant human ANGPT2 protein with C-terminal human Fc tag |
| Background: The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 49.94 kDa after removal of the signal peptide. |
| Molecular Characterization: ANGPT2(Lys275-Phe496) hFc(Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
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