Email: info@neweastbio.com  |  Call: 6109452007

Distributors  ·  How to Order  ·  Contact Us

China
Awaiting product image

Anti-MMAE Monoclonal antibody (11B2)

$549.00

Anti-MMAE Monoclonal antibody (11B2)

Cat. #:   26102
Size:  100 µL
Description:   Anti-MMAE Monoclonal antibody(11B2)
Background: Monomethyl auristatin E (MMAE), a potent mitotic inhibitor derived from dolastatin 10, plays a pivotal role in antibody-drug conjugates (ADCs) for cancer therapy. ADCs precisely target cancer cells, minimizing collateral damage. However, ADC development requires thorough pharmacokinetic and safety assessments. Our specialized anti-MMAE antibodies streamline this process, facilitating PK analysis and safety evaluation. These antibodies are crucial tools for optimizing ADCs, ensuring their effectiveness and safety in revolutionizing cancer treatment.
Immunogen:   Monomethyl auristatin E
Applications:   ELISA
Recommended Dilutions:   ELISA 1:5000-10000
Concentration:    1 mg/ml
Clone ID:    11B2
Host Species:   Rabbit
Clonality:   Monoclonal
Isotype:    Rabbit IgG
Purity:   Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution:Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage Conditions:   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
image.png
Figure 1. Elisa plates were pre-coated with IgG-MMAE (0.2μg/per well). Serial diluted anti-MMAE monoclonal antibody (26102) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-MMAE monoclonal antibody binding with IgG-MMAE is 2.538 ng/ml.
SKU: 26102
Category:

Related products