IL-6 (DMC419) IgG1 Chimeric mAb
$565.00
| Cat.#: 28213 |
| Product Name: Anti-IL-6(DMC419) IgG1 Chimeric Monoclonal Antibody |
| Synonyms: IL6; Interleukin-6; BSF2; HSF; IFNB2 |
| Description: Anti-IL-6 antibody(DMC419) IgG1 Chimeric Monoclonal Antibody |
| Background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition; the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation; where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor; alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states; including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. |
| Applications: Flow Cyt |
| Recommended Dilutions: Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit:Human Fc chimeric IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human IL-6 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 Figure 1. Flow cytometry analysis with Anti-IL-6 (DMC419) on Expi293 cells transfected with human IL-6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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