FGFR4 (DMC460) IgG1 Chimeric mAb
$565.00
| Cat.#: 28236 |
| Product Name: Anti-FGFR4(DMC460) IgG1 Chimeric Monoclonal Antibody |
| Synonyms: CD334; JTK2; TKF |
| Description: Anti-FGFR4 antibody(DMC460) IgG1 Chimeric Monoclonal Antibody |
| Background: The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. [provided by RefSeq; Aug 2017] |
| Applications: Flow Cyt |
| Recommended Dilutions: Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit:Human Fc chimeric IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human FGFR4 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 Figure 1. Flow cytometry analysis with Anti-FGFR4 (DMC460) on Expi293 cells transfected with human FGFR4 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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