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CB1 (DM144) Rabbit mAb

$565.00

Cat.#:   28488
Product Name:   Anti-CB1(DM144) Rabbit Monoclonal Antibody
Synonyms:   CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
Description:    Anti-CB1 antibody(DM144) Rabbit Monoclonal Antibody
Background:    This gene encodes one of two cannabinoid receptors. The cannabinoids; principally delta-9-tetrahydrocannabinol and synthetic analogs; are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family; which inhibit adenylate cyclase activity in a dose-dependent; stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CB1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human CB1 protein, hFc tagged protein 11310 can bind Rabbit anti-CB1 monoclonal antibody (clone: DM144) in a linear range of 5-200 ng/ml.

Figure 2. Flow cytometry analysis with Anti-CB1 (DM144) on Expi293 cells transfected with human CB1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

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